| Gene Information | |
|---|---|
| Gene Name | ACAA1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 424 |
| Protein Names | 3-ketoacyl-CoA thiolase, peroxisomal (EC 2.3.1.16) (Acetyl-CoA C-myristoyltransferase) (EC 2.3.1.155) (Acetyl-CoA acyltransferase) (EC 2.3.1.9) (Beta-ketothiolase) (Peroxisomal 3-oxoacyl-CoA thiolase) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000060971 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | P09110 |
| Gene Card | ACAA1 |
| Uniprot ID | P09110 |
| Pfam | PF02803; PF00108 |
| In ASD | no |
| Allosteric Prediction | yes (0.121728376) |
| Ortholog in Animals | Alpaca_ ACAA1 ( ortholog_one2one ) Dog_ ACAA1 ( ortholog_one2one ) Macaque_ ACAA1 ( ortholog_one2one ) Mouse_ Acaa1a ( ortholog_one2many ) Mouse_ Acaa1b ( ortholog_one2many ) Pig_ ACAA1 ( ortholog_one2one ) Rat_ Acaa1a ( ortholog_one2many ) Rat_ Acaa1b ( ortholog_one2many ) Rabbit_ ACAA1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | HADHB, ACAA2, ACAT2, ACAT1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.014286(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2IIK (X-ray 2.55A ) |
| DBSNP | rs156265 rs2229528 |
| Subcellular location [CC] | Peroxisome {ECO:0000269|PubMed:22057399, ECO:0000269|PubMed:25538232}. Note=Transported into peroxisomes following association with PEX7. {ECO:0000269|PubMed:22057399, ECO:0000269|PubMed:25538232}. |
| Mouse PG classification | NA |
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