| Gene Information | |
|---|---|
| Gene Name | OCT6 |
| Organism | Homo sapiens (Human) |
| Gene Length | 577 |
| Protein Names | Solute carrier family 22 member 16 (Carnitine transporter 2) (CT2) (Fly-like putative transporter 2) (FLIPT2) (Flipt 2) (Organic cation transporter OKB1) (Organic cation/carnitine transporter 6) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q86VW1 |
| Gene Card | SLC22A16 |
| Uniprot ID | Q86VW1 |
| Pfam | PF00083 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Widely expressed at low levels in adult tissues and fetal brain, lung, liver and kidney. Expressed in testis and epididymis (at protein level). Expressed at lower levels in bone marrow and fetal liver. Expressed in hematopoietic cells, including CD34(+) leukocytes and leukemia cells. Abundantly expressed in ovarian cancer clear-cell adenocarcinoma. Expressed in endometrium (at protein level); highly expressed during the normal secretory phase, but expression is significantly reduced in the proliferative phase. {ECO:0000269|PubMed:12089149, ECO:0000269|PubMed:12372408, ECO:0000269|PubMed:12384147, ECO:0000269|PubMed:15963465, ECO:0000269|PubMed:17197897, ECO:0000269|PubMed:17581421}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs714368 rs723685 rs12210538 rs35948062 |
| Subcellular location [CC] | Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Cell membrane {ECO:0000269|PubMed:12089149}. Note=Detected in the plasma membrane of Sertoli cells and in the luminal membrane of epithelial cells in the epididymis. |
| Mouse PG classification | NA |
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