Gene Information
Gene NameUBE1C
OrganismHomo sapiens (Human)
Gene Length463
Protein NamesNEDD8-activating enzyme E1 catalytic subunit (EC 6.2.1.64) (NEDD8-activating enzyme E1C) (Ubiquitin-activating enzyme E1C) (Ubiquitin-like modifier-activating enzyme 3) (Ubiquitin-activating enzyme 3)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBQ8TBC4
Gene CardUBA3
Uniprot IDQ8TBC4
PfamPF08825; PF00899
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityUbiquitously expressed. {ECO:0000269|PubMed:10207026}.
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.05(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 1R4M  (X-ray  3.00A  1R4N  (X-ray  3.60A  1TT5  (X-ray  2.60A  1Y8X  (X-ray  2.40A  1YOV  (X-ray  2.60A  2LQ7  (NMR  2NVU  (X-ray  2.80A  3DBH  (X-ray  2.85A  3DBL  (X-ray  2.90A  3DBR  (X-ray  3.05A  3FN1  (X-ray  2.50A  3GZN  (X-ray  3.00A  5JJM  (X-ray  2.15A 
DBSNP rs17852113 
Subcellular location [CC]NA
Mouse PG classificationNA
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