| Gene Information | |
|---|---|
| Gene Name | CTSZ |
| Organism | Homo sapiens (Human) |
| Gene Length | 303 |
| Protein Names | Cathepsin Z (EC 3.4.18.1) (Cathepsin P) (Cathepsin X) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000101160 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9UBR2 |
| Gene Card | CTSZ |
| Uniprot ID | Q9UBR2 |
| Pfam | PF00112 |
| In ASD | no |
| Allosteric Prediction | no (-0.068512119) |
| Ortholog in Animals | Alpaca_ CTSZ ( ortholog_one2one ) Dog_ CTSZ ( ortholog_one2one ) GuineaPig_ CTSZ ( ortholog_one2one ) Macaque_ CTSZ ( ortholog_one2one ) Mouse_ Ctsz ( ortholog_one2one ) Pig_ CTSZ ( ortholog_one2one ) Rat_ Ctsz ( ortholog_one2one ) Rabbit_ CTSZ ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CTSL, CTSV, CTSK, CTSH, TINAGL1, CTSO, CTSW, CTSF, TINAG, CTSB, CTSC, CTSS |
| Tissue | NA |
| Tissue Specificity | Widely expressed. {ECO:0000269|PubMed:10653163}. |
| Pharmacological Animal Models | NULL(Chimpanzee);0.001000(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1DEU (X-ray 1.70A ) 1EF7 (X-ray 2.67A ) |
| DBSNP | rs778998634 rs34069356 |
| Subcellular location [CC] | Lysosome. |
| Mouse PG classification | NA |
| click here to return to the previous page | |