| Gene Information | |
|---|---|
| Gene Name | HTR6 |
| Organism | Homo sapiens (Human) |
| Gene Length | 440 |
| Protein Names | 5-hydroxytryptamine receptor 6 (5-HT-6) (5-HT6) (Serotonin receptor 6) |
| Target Name | 5-hydroxytryptamine receptor 6 |
| Target Type | NA |
| Gene Age | 55 ( ENSG00000158748 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P50406 |
| Gene Card | HTR6 |
| Uniprot ID | P50406 |
| Pfam | PF00001 |
| In ASD | no |
| Allosteric Prediction | yes (1.256865846) |
| Ortholog in Animals | Alpaca_ HTR6 ( ortholog_one2one ) GuineaPig_ HTR6 ( ortholog_one2one ) Macaque_ HTR6 ( ortholog_one2one ) Mouse_ Htr6 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | HTR7, HTR5A, HTR1E, HTR1B, HTR1F, HTR2C, HTR2A, HTR2B |
| Tissue | caudate.nucleus, putamen |
| Tissue Specificity | Expressed in several human brain regions, most prominently in the caudate nucleus. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7XTB (EM 3.30A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane; Multi-pass membrane protein. |
| Mouse PG classification | NA |
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