Gene Information
Gene NameUBASH3B
OrganismHomo sapiens (Human)
Gene Length649
Protein NamesUbiquitin-associated and SH3 domain-containing protein B (EC 3.1.3.48) (Cbl-interacting protein p70) (Suppressor of T-cell receptor signaling 1) (STS-1) (T-cell ubiquitin ligand 2) (TULA-2) (Tyrosine-protein phosphatase STS1/TULA2)
Target NameNA
Target TypeNA
Gene Age810 ( ENSG00000154127 )
Evolutionary StageEumetazoa
AlphaFoldDBQ8TF42
Gene CardUBASH3B
Uniprot IDQ8TF42
PfamPF00300; PF14604; PF00627
In ASDno
Allosteric Predictionyes (0.269482375)
Ortholog in AnimalsAlpaca_ UBASH3B ( ortholog_one2one )
Dog_ UBASH3B ( ortholog_one2one )
GuineaPig_ UBASH3B ( ortholog_one2one )
Macaque_ UBASH3B ( ortholog_one2one )
Mouse_ Ubash3b ( ortholog_one2one )
Pig_ UBASH3B ( ortholog_one2one )
Rat_ Ubash3b ( ortholog_one2one )
Rabbit_ UBASH3B ( ortholog_one2one )
OhnologsUBASH3A
ParalogsUBASH3A
Tissueplacenta, spleen, cerebellar.hemisphere, cerebellum
Tissue SpecificityNA
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);0.001445(Rat);0.028571(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 2CPW  (NMR  2E5K  (NMR  5VR6  (X-ray  1.87A  5W5G  (X-ray  2.48A 
DBSNP rs12790613  rs35343548 
Subcellular location [CC]Cytoplasm {ECO:0000250}. Nucleus {ECO:0000305}.
Mouse PG classificationNA
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