| Gene Information | |
|---|---|
| Gene Name | IDH3B |
| Organism | Homo sapiens (Human) |
| Gene Length | 385 |
| Protein Names | Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial (Isocitric dehydrogenase subunit beta) (NAD(+)-specific ICDH subunit beta) |
| Target Name | isocitrate dehydrogenase [nad] subunit beta, mitochondrial |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000101365 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O43837 |
| Gene Card | IDH3B |
| Uniprot ID | O43837 |
| Pfam | PF00180 |
| In ASD | no |
| Allosteric Prediction | yes (0.244367511) |
| Ortholog in Animals | Alpaca_ IDH3B ( ortholog_one2one ) Dog_ IDH3B ( ortholog_one2many ) GuineaPig_ IDH3B ( ortholog_one2one ) Macaque_ IDH3B ( ortholog_one2one ) Mouse_ Idh3b ( ortholog_one2one ) Pig_ IDH3B ( ortholog_one2one ) Rat_ Idh3b ( ortholog_one2one ) Rabbit_ IDH3B ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | IDH3G, IDH3A |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);0.001000(Mouse);0.054031(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6KDE (X-ray 3.00A ) 6KDF (X-ray 3.05A ) 6KDY (X-ray 3.02A ) 6KE3 (X-ray 3.31A ) 7CE3 (X-ray 3.47A ) |
| DBSNP | rs3178817 rs137853020 rs11542741 rs8296 |
| Subcellular location [CC] | Mitochondrion. |
| Mouse PG classification | NA |
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