| Gene Information | |
|---|---|
| Gene Name | FRY |
| Organism | Homo sapiens (Human) |
| Gene Length | 3013 |
| Protein Names | Protein furry homolog |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 424 ( ENSG00000073910 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | NA |
| Gene Card | FRY |
| Uniprot ID | Q5TBA9 |
| Pfam | PF19421; PF14225; PF14228; PF14222 |
| In ASD | no |
| Allosteric Prediction | no (-1.086197677) |
| Ortholog in Animals | Alpaca_ FRY ( ortholog_one2one ) Dog_ FRY ( ortholog_one2one ) GuineaPig_ FRY ( ortholog_one2one ) Macaque_ FRY ( ortholog_one2one ) Mouse_ Fry ( ortholog_one2one ) Pig_ FRY ( ortholog_one2one ) Rat_ Fry ( ortholog_one2one ) Rabbit_ FRY ( ortholog_one2one ) |
| Ohnologs | FRYL |
| Paralogs | FRYL |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);0.070650(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2806639 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:22753416}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:22753416}. Cytoplasm, cytoskeleton, spindle pole {ECO:0000269|PubMed:22753416}. Note=Distributed diffusely throughout the cytoplasm in interphase. Localizes to the separating centrosomes in prophase, to the spindle poles and spindle microtubules in prometaphase to metaphase, to spindle microtubules in anaphase and to the distal sections of the midbody in cytokinesis. Colocalizes with PLK1 to separating centrosomes and spindle poles from prophase to metaphase in mitosis, but not in other stages of the cell cycle. |
| Mouse PG classification | NA |
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