| Gene Information | |
|---|---|
| Gene Name | UAF1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 677 |
| Protein Names | WD repeat-containing protein 48 (USP1-associated factor 1) (WD repeat endosomal protein) (p80) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q8TAF3 |
| Gene Card | WDR48 |
| Uniprot ID | Q8TAF3 |
| Pfam | PF11816; PF00400 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. {ECO:0000269|PubMed:12196293}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.05(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5CVL (X-ray 3.00A ) 5CVN (X-ray 3.36A ) 5CVO (X-ray 3.88A ) 5K1A (X-ray 2.30A ) 5K1B (X-ray 3.30A ) 5K1C (X-ray 3.00A ) 5L8E (X-ray 2.30A ) 5L8W (X-ray 2.79A ) 6JLQ (X-ray 3.10A ) 7AY0 (X-ray 3.60A ) 7AY1 (EM 3.70A ) 7AY2 (X-ray 3.20A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:18032488}. Cytoplasm {ECO:0000269|PubMed:12196293, ECO:0000269|PubMed:18032488}. Lysosome {ECO:0000269|PubMed:12196293}. Late endosome {ECO:0000269|PubMed:12196293}. Note=Mainly in cytoplasmic compartments (PubMed:12196293, PubMed:18032488). In case of infection by papillomavirus HPV11, translocates to the nucleus via its interaction with papillomavirus HPV11 (PubMed:18032488). {ECO:0000269|PubMed:12196293, ECO:0000269|PubMed:18032488}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |