| Gene Information | |
|---|---|
| Gene Name | UACA |
| Organism | Homo sapiens (Human) |
| Gene Length | 1416 |
| Protein Names | Uveal autoantigen with coiled-coil domains and ankyrin repeats |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000137831 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q9BZF9 |
| Gene Card | UACA |
| Uniprot ID | Q9BZF9 |
| Pfam | PF12796 |
| In ASD | no |
| Allosteric Prediction | no (-0.820815452) |
| Ortholog in Animals | Alpaca_ UACA ( ortholog_one2one ) Dog_ UACA ( ortholog_one2one ) GuineaPig_ UACA ( ortholog_one2one ) Macaque_ UACA ( ortholog_one2one ) Mouse_ Uaca ( ortholog_one2one ) Pig_ UACA ( ortholog_one2one ) Rat_ Uaca ( ortholog_one2one ) Rabbit_ UACA ( ortholog_one2one ) |
| Ohnologs | RAI14 |
| Paralogs | ASB2, ANKRD24 |
| Tissue | NA |
| Tissue Specificity | Highly expressed in skeletal muscle, heart, kidney and pancreas. Expressed in choroid, retina and epidermal melanocytes. Expressed in eye muscles and thyroid follicular cells. {ECO:0000269|PubMed:11162650, ECO:0000269|PubMed:15358194}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs3743315 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:15358194}. Cytoplasm {ECO:0000269|PubMed:15358194}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:15358194}. Note=Expressed diffusely in cytoplasm. |
| Mouse PG classification | NA |
| click here to return to the previous page | |