Gene Information
Gene NameU2AF2
OrganismHomo sapiens (Human)
Gene Length475
Protein NamesSplicing factor U2AF 65 kDa subunit (U2 auxiliary factor 65 kDa subunit) (hU2AF(65)) (hU2AF65) (U2 snRNP auxiliary factor large subunit)
Target NameNA
Target TypeNA
Gene Age987 ( ENSG00000063244 )
Evolutionary StageEukaryota
AlphaFoldDBP26368
Gene CardU2AF2
Uniprot IDP26368
PfamPF00076
In ASDno
Allosteric Predictionno (-0.520825051)
Ortholog in AnimalsAlpaca_ U2AF2 ( ortholog_one2one )
Dog_ U2AF2 ( ortholog_one2one )
GuineaPig_ U2AF2 ( ortholog_one2one )
Macaque_ U2AF2 ( ortholog_one2one )
Mouse_ U2af2 ( ortholog_one2one )
Pig_ U2AF2 ( ortholog_one2one )
Rat_ U2af2 ( ortholog_one2one )
OhnologsNA
ParalogsRBMX2, CSTF2T, ZCRB1, CSTF2, UHMK1
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 1JMT  (X-ray  2.20A  1O0P  (NMR  1OPI  (NMR  1U2F  (NMR  2G4B  (X-ray  2.50A  2HZC  (X-ray  1.47A  2M0G  (NMR  2U2F  (NMR  2YH0  (NMR  2YH1  (NMR  3VAF  (X-ray  2.49A  3VAG  (X-ray  2.19A  3VAH  (X-ray  2.50A  3VAI  (X-ray  2.20A  3VAJ  (X-ray  1.90A  3VAK  (X-ray  2.17A  3VAL  (X-ray  2.50A  3VAM  (X-ray  2.40A  4FXW  (X-ray  2.29A  4TU7  (X-ray  2.09A  4TU8  (X-ray  1.92A  4TU9  (X-ray  1.99A  5EV1  (X-ray  2.04A  5EV2  (X-ray  1.86A  5EV3  (X-ray  1.50A  5EV4  (X-ray  1.57A  5W0G  (X-ray  1.07A  5W0H  (X-ray  1.11A  6TR0  (NMR  6XLV  (X-ray  1.40A  6XLW  (X-ray  1.50A  6XLX  (X-ray  1.70A  7S3A  (X-ray  1.48A  7S3B  (X-ray  1.89A  7S3C  (X-ray  1.51A  7SN6  (X-ray  1.80A 
DBSNP NA 
Subcellular location [CC]Nucleus.
Mouse PG classificationNA
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