| Gene Information | |
|---|---|
| Gene Name | U2AF1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 240 |
| Protein Names | Splicing factor U2AF 35 kDa subunit (U2 auxiliary factor 35 kDa subunit) (U2 small nuclear RNA auxiliary factor 1) (U2 snRNP auxiliary factor small subunit) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1714 ( ENSG00000160201 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q01081 |
| Gene Card | U2AF1 |
| Uniprot ID | Q01081 |
| Pfam | PF00076; PF00642 |
| In ASD | no |
| Allosteric Prediction | no (-0.529665868) |
| Ortholog in Animals | Alpaca_ U2AF1 ( ortholog_one2one ) Dog_ U2AF1 ( ortholog_one2one ) GuineaPig_ U2AF1 ( ortholog_one2one ) Macaque_ U2AF1 ( ortholog_one2one ) Mouse_ U2af1 ( ortholog_one2one ) Pig_ U2AF1 ( ortholog_one2one ) Rat_ U2af1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | U2AF1L4, ZRSR2 |
| Tissue | bone.marrow |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);0.001000(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1JMT (X-ray 2.20A ) |
| DBSNP | rs371769427 rs371769427 rs371246226 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:15096518}. Nucleus speckle {ECO:0000269|PubMed:15096518, ECO:0000269|PubMed:25311244}. |
| Mouse PG classification | NA |
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