| Gene Information | |
|---|---|
| Gene Name | TYK1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 864 |
| Protein Names | Leukocyte tyrosine kinase receptor (EC 2.7.10.1) (Protein tyrosine kinase 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P29376 |
| Gene Card | LTK |
| Uniprot ID | P29376 |
| Pfam | PF07714 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in non-hematopoietic cell lines and T- and B-cell lines. {ECO:0000269|PubMed:2156206}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7NX0 (X-ray 1.95A ) 7NX1 (X-ray 1.30A ) |
| DBSNP | rs2305030 rs55683312 rs35932273 rs148513655 rs55876255 rs55900837 rs76282169 rs56367146 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:34646012}; Single-pass type I membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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