| Gene Information | |
|---|---|
| Gene Name | TCF12 |
| Organism | Homo sapiens (Human) |
| Gene Length | 682 |
| Protein Names | Transcription factor 12 (TCF-12) (Class B basic helix-loop-helix protein 20) (bHLHb20) (DNA-binding protein HTF4) (E-box-binding protein) (Transcription factor HTF-4) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000140262 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q99081 |
| Gene Card | TCF12 |
| Uniprot ID | Q99081 |
| Pfam | PF00010 |
| In ASD | no |
| Allosteric Prediction | no (-0.698872476) |
| Ortholog in Animals | Alpaca_ TCF12 ( ortholog_one2one ) Dog_ TCF12 ( ortholog_one2one ) GuineaPig_ TCF12 ( ortholog_one2one ) Macaque_ TCF12 ( ortholog_one2one ) Mouse_ Tcf12 ( ortholog_one2one ) Pig_ TCF12 ( ortholog_one2one ) Rat_ Tcf12 ( ortholog_one2one ) Rabbit_ TCF12 ( ortholog_one2one ) |
| Ohnologs | TCF3, TCF4 |
| Paralogs | TCF4, TCF3 |
| Tissue | NA |
| Tissue Specificity | Expressed in several tissues and cell types including skeletal muscle, thymus, and a B-cell line. |
| Pharmacological Animal Models | 0.072363(Chimpanzee);0.072270(Mouse);NULL(Rat);0.046506(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2KNH (NMR - ) 4JOL (X-ray 2.91A ) |
| DBSNP | rs12442879 rs36060670 rs886037641 |
| Subcellular location [CC] | Nucleus. |
| Mouse PG classification | LPG |
| click here to return to the previous page | |