| Gene Information | |
|---|---|
| Gene Name | TWIST1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 202 |
| Protein Names | Twist-related protein 1 (Class A basic helix-loop-helix protein 38) (bHLHa38) (H-twist) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 55 ( ENSG00000122691 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q15672 |
| Gene Card | TWIST1 |
| Uniprot ID | Q15672 |
| Pfam | PF00010 |
| In ASD | no |
| Allosteric Prediction | yes (0.104771224) |
| Ortholog in Animals | Alpaca_ TWIST1 ( ortholog_one2one ) Dog_ TWIST1 ( ortholog_one2one ) Mouse_ Twist1 ( ortholog_one2one ) Pig_ TWIST1 ( ortholog_one2one ) Rat_ Twist1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | TWIST2, SCX, PTF1A, FERD3L, BHLHA9, FIGLA, TCF23, HAND2, MSC, TCF15, HAND1, TCF24, TCF21 |
| Tissue | adipose.tissue, placenta |
| Tissue Specificity | Subset of mesodermal cells. |
| Pharmacological Animal Models | 0.023713(Chimpanzee);0.001000(Mouse);0.001000(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2MJV (NMR - ) |
| DBSNP | rs545987863 rs575299986 rs1554442016 rs1554442016 rs104894057 rs121909189 rs104894059 rs121909190 rs121909191 |
| Subcellular location [CC] | Nucleus. |
| Mouse PG classification | HPG |
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