| Gene Information | |
|---|---|
| Gene Name | TWA1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 228 |
| Protein Names | Glucose-induced degradation protein 8 homolog (Two hybrid-associated protein 1 with RanBPM) (Twa1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q9NWU2 |
| Gene Card | GID8 |
| Uniprot ID | Q9NWU2 |
| Pfam | PF10607; PF08513 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Up-regulated in colorectal cancer tissues (at protein level). {ECO:0000269|PubMed:28829046}. |
| Pharmacological Animal Models | 0.054143(Chimpanzee);0.033633(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7NSC (EM 3.30A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:17467196, ECO:0000269|PubMed:24143168, ECO:0000269|PubMed:28829046}. Nucleus {ECO:0000269|PubMed:12559565, ECO:0000269|PubMed:17467196, ECO:0000269|PubMed:24143168, ECO:0000269|PubMed:28829046, ECO:0000269|PubMed:29911972}. Note=Localizes in the cytoplasm in the absence of Wnt stimulation and in the nucleus in the presence of Wnt stimulation. {ECO:0000269|PubMed:28829046}. |
| Mouse PG classification | NA |
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