| Gene Information | |
|---|---|
| Gene Name | TUT4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1644 |
| Protein Names | Terminal uridylyltransferase 4 (TUTase 4) (EC 2.7.7.52) (Zinc finger CCHC domain-containing protein 11) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000134744 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q5TAX3 |
| Gene Card | TUT4 |
| Uniprot ID | Q5TAX3 |
| Pfam | PF01909; PF03828; PF19088; PF00098 |
| In ASD | no |
| Allosteric Prediction | no (-1.000325025) |
| Ortholog in Animals | Alpaca_ TUT4 ( ortholog_one2one ) Dog_ TUT4 ( ortholog_one2one ) GuineaPig_ TUT4 ( ortholog_one2one ) Macaque_ TUT4 ( ortholog_one2one ) Mouse_ Tut4 ( ortholog_one2one ) Pig_ TUT4 ( ortholog_one2one ) Rat_ Tut4 ( ortholog_one2one ) Rabbit_ TUT4 ( ortholog_one2one ) |
| Ohnologs | TUT7 |
| Paralogs | TENT2, MTPAP, TUT1, TUT7 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6IW6 (X-ray 2.40A ) |
| DBSNP | rs12127732 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:16643855}. Cytoplasm {ECO:0000269|PubMed:16643855, ECO:0000269|PubMed:19703396, ECO:0000269|PubMed:25480299}. Cytoplasm, Cytoplasmic ribonucleoprotein granule {ECO:0000269|PubMed:30122351}. Note=Mainly cytoplasmic (PubMed:19703396, PubMed:25480299). Translocates into the cytoplasm following treatment of the cell with LPS (PubMed:16643855). Co-enriched in cytoplasmic foci with MOV10 (PubMed:30122351). {ECO:0000269|PubMed:30122351}. |
| Mouse PG classification | NA |
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