| Gene Information | |
|---|---|
| Gene Name | TUBB8 |
| Organism | Homo sapiens (Human) |
| Gene Length | 444 |
| Protein Names | Tubulin beta-8 chain (Tubulin beta 8 class VIII) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 55 ( ENSG00000261456 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | Q3ZCM7 |
| Gene Card | TUBB8 |
| Uniprot ID | Q3ZCM7 |
| Pfam | PF00091; PF03953 |
| In ASD | no |
| Allosteric Prediction | no (-0.230218101) |
| Ortholog in Animals | Alpaca_ TUBB8 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | TUBB, TUBA4B, TUBA8, TUBA4A, TUBB6, TUBB3, TUBAL3, TUBG2, TUBE1, TUBB1, TUBB4B, TUBB4A, TUBA1B, TUBA1A, TUBA1C, TUBA3E, TUBA3C, TUBA3D, TUBD1, TUBG1, TUBB2A, TUBB2B, TUBB8B |
| Tissue | NA |
| Tissue Specificity | Expressed at a high level in oocytes, at different stages of development. {ECO:0000269|PubMed:26789871}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs869025273 rs869025609 rs781853492 rs869025271 rs1057520306 rs782269374 rs869025610 rs782486119 rs869025612 rs4880608 rs1270068662 rs869025611 rs869025272 |
| Subcellular location [CC] | Cytoplasm, cytoskeleton {ECO:0000269|PubMed:26789871}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:26789871}. |
| Mouse PG classification | NA |
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