| Gene Information | |
|---|---|
| Gene Name | TPI1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 249 |
| Protein Names | Triosephosphate isomerase (TIM) (EC 5.3.1.1) (Methylglyoxal synthase) (EC 4.2.3.3) (Triose-phosphate isomerase) |
| Target Name | triosephosphate isomerase |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000111669 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | P60174 |
| Gene Card | TPI1 |
| Uniprot ID | P60174 |
| Pfam | PF00121 |
| In ASD | no |
| Allosteric Prediction | yes (0.712685794) |
| Ortholog in Animals | Alpaca_ TPI1 ( ortholog_one2many ) Dog_ TPI1 ( ortholog_one2one ) GuineaPig_ TPI1 ( ortholog_one2one ) Macaque_ TPI1 ( ortholog_one2one ) Mouse_ Tpi1 ( ortholog_one2one ) Pig_ TPI1 ( ortholog_one2one ) Rat_ RGD1563601 ( ortholog_one2many ) Rat_ Tpi1 ( ortholog_one2many ) Rat_ AC094212.1 ( ortholog_one2many ) Rabbit_ TPI1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.221534(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1HTI (X-ray 2.80A ) 1KLG (X-ray 2.40A ) 1KLU (X-ray 1.93A ) 1WYI (X-ray 2.20A ) 2IAM (X-ray 2.80A ) 2IAN (X-ray 2.80A ) 2JK2 (X-ray 1.70A ) 2VOM (X-ray 1.85A ) 4BR1 (X-ray 1.90A ) 4E41 (X-ray 2.60A ) 4POC (X-ray 1.60A ) 4POD (X-ray 1.99A ) 4UNK (X-ray 2.00A ) 4UNL (X-ray 1.50A ) 4ZVJ (X-ray 1.70A ) 6C2G (X-ray 2.30A ) 6D43 (X-ray 2.04A ) 6NLH (X-ray 2.20A ) 6UP1 (X-ray 1.83A ) 6UP5 (X-ray 1.92A ) 6UP8 (X-ray 2.00A ) 6UPF (X-ray 1.65A ) 7RDE (X-ray 1.31A ) |
| DBSNP | rs121964848 rs121964845 rs121964846 rs188138723 rs121964849 rs1555132614 rs121964847 |
| Subcellular location [CC] | Cytoplasm {ECO:0000255|PROSITE-ProRule:PRU10127}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |