| Gene Information | |
|---|---|
| Gene Name | TTF1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 905 |
| Protein Names | Transcription termination factor 1 (TTF-1) (RNA polymerase I termination factor) (Transcription termination factor I) (TTF-I) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000125482 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q15361 |
| Gene Card | TTF1 |
| Uniprot ID | Q15361 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | yes (0.464170208) |
| Ortholog in Animals | Alpaca_ TTF1 ( ortholog_one2one ) Dog_ TTF1 ( ortholog_one2one ) Macaque_ TTF1 ( ortholog_one2one ) Mouse_ Ttf1 ( ortholog_one2one ) Pig_ TTF1 ( ortholog_one2one ) Rat_ Ttf1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | MYBL1, DMTF1, SNAPC4, CDC5L, MYBL2, MYB |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs11550314 rs8999 rs3739914 rs3739915 rs3739916 rs12336746 rs1752676 |
| Subcellular location [CC] | Nucleus {ECO:0000250|UniProtKB:Q62187}. Nucleus, nucleolus {ECO:0000250|UniProtKB:Q62187}. Nucleus, nucleoplasm {ECO:0000250|UniProtKB:Q62187}. Note=May be localized to the nucleolus in an NPM1/B23-dependent manner. May be displaced from the nucleolus into the nucleoplasm in an CDKN2A/ARF-dependent manner. May shuttle back and forth from nucleoplasm to nucleolus. {ECO:0000250|UniProtKB:Q62187}. |
| Mouse PG classification | NA |
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