| Gene Information | |
|---|---|
| Gene Name | TTC8 |
| Organism | Homo sapiens (Human) |
| Gene Length | 541 |
| Protein Names | Tetratricopeptide repeat protein 8 (TPR repeat protein 8) (Bardet-Biedl syndrome 8 protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000165533 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q8TAM2 |
| Gene Card | TTC8 |
| Uniprot ID | Q8TAM2 |
| Pfam | PF13176 |
| In ASD | no |
| Allosteric Prediction | no (-0.77981211) |
| Ortholog in Animals | Alpaca_ TTC8 ( ortholog_one2one ) Dog_ TTC8 ( ortholog_one2one ) GuineaPig_ TTC8 ( ortholog_one2one ) Macaque_ TTC8 ( ortholog_one2one ) Mouse_ Ttc8 ( ortholog_one2one ) Pig_ TTC8 ( ortholog_one2one ) Rat_ Ttc8 ( ortholog_one2one ) Rabbit_ TTC8 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | BBS4, OGT, CFAP70, TTC34, TTC6, TMTC1, TTC16, TMTC4, TTC13, TTC7A, TMTC2, TMTC3, IFT88, TTC7B |
| Tissue | NA |
| Tissue Specificity | Widely expressed. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:17574030}. Cell projection, cilium membrane {ECO:0000269|PubMed:17574030}. Cytoplasm {ECO:0000269|PubMed:22072986}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite {ECO:0000269|PubMed:17574030}. Cell projection, cilium {ECO:0000250|UniProtKB:Q8VD72}. |
| Mouse PG classification | HPG |
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