| Gene Information | |
|---|---|
| Gene Name | CXCL11 |
| Organism | Homo sapiens (Human) |
| Gene Length | 94 |
| Protein Names | C-X-C motif chemokine 11 (Beta-R1) (H174) (Interferon gamma-inducible protein 9) (IP-9) (Interferon-inducible T-cell alpha chemoattractant) (I-TAC) (Small-inducible cytokine B11) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 244 ( ENSG00000169248 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | O14625 |
| Gene Card | CXCL11 |
| Uniprot ID | O14625 |
| Pfam | PF00048 |
| In ASD | no |
| Allosteric Prediction | no (-0.047949848) |
| Ortholog in Animals | Alpaca_ CXCL11 ( ortholog_one2one ) Dog_ CXCL11 ( ortholog_one2one ) GuineaPig_ CXCL11 ( ortholog_one2one ) Macaque_ CXCL11 ( ortholog_one2one ) Pig_ CXCL11 ( ortholog_one2one ) Rat_ Cxcl11 ( ortholog_one2one ) Rabbit_ CXCL11 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CXCL8, CXCL5, CXCL2, CXCL3, CXCL10, CXCL9, CXCL1, CXCL13, CXCL6, PF4, PF4V1, PPBP |
| Tissue | NA |
| Tissue Specificity | High levels in peripheral blood leukocytes, pancreas and liver astrocytes. Moderate levels in thymus, spleen and lung. Low levels in placenta, prostate and small intestine. Also found in epidermal basal layer keratinocytes in skin disorders. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1RJT (NMR - ) |
| DBSNP | rs4859596 |
| Subcellular location [CC] | Secreted. |
| Mouse PG classification | NA |
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