| Gene Information | |
|---|---|
| Gene Name | BST1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 318 |
| Protein Names | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 (EC 3.2.2.6) (ADP-ribosyl cyclase 2) (Bone marrow stromal cell antigen 1) (BST-1) (Cyclic ADP-ribose hydrolase 2) (cADPr hydrolase 2) (CD antigen CD157) |
| Target Name | adp-ribosyl cyclase 2 |
| Target Type | NA |
| Gene Age | 382 ( ENSG00000109743 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q10588 |
| Gene Card | BST1 |
| Uniprot ID | Q10588 |
| Pfam | PF02267 |
| In ASD | no |
| Allosteric Prediction | no (-0.097979128) |
| Ortholog in Animals | Alpaca_ BST1 ( ortholog_one2one ) Dog_ BST1 ( ortholog_one2one ) Macaque_ BST1 ( ortholog_one2one ) Mouse_ Bst1 ( ortholog_one2one ) Pig_ BST1 ( ortholog_one2one ) Rat_ Bst1 ( ortholog_one2one ) Rabbit_ BST1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CD38 |
| Tissue | NA |
| Tissue Specificity | Expressed in various tissues including placenta, lung, liver and kidney. {ECO:0000269|PubMed:8202488}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1ISF (X-ray 2.50A ) 1ISG (X-ray 2.60A ) 1ISH (X-ray 2.40A ) 1ISI (X-ray 2.10A ) 1ISJ (X-ray 2.30A ) 1ISM (X-ray 3.00A ) |
| DBSNP | rs2302466 rs6840615 rs2302465 rs2302464 |
| Subcellular location [CC] | Cell membrane; Lipid-anchor, GPI-anchor {ECO:0000269|PubMed:8202488}. |
| Mouse PG classification | NA |
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