| Gene Information | |
|---|---|
| Gene Name | TSPYL2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 693 |
| Protein Names | Testis-specific Y-encoded-like protein 2 (TSPY-like protein 2) (Cell division autoantigen 1) (Cutaneous T-cell lymphoma-associated antigen se20-4) (CTCL-associated antigen se20-4) (Differentially-expressed nucleolar TGF-beta1 target protein) (Nuclear protein of 79 kDa) (NP79) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 132 ( ENSG00000184205 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | Q9H2G4 |
| Gene Card | TSPYL2 |
| Uniprot ID | Q9H2G4 |
| Pfam | PF00956 |
| In ASD | no |
| Allosteric Prediction | no (-0.640037543) |
| Ortholog in Animals | Alpaca_ TSPYL2 ( ortholog_one2one ) GuineaPig_ TSPYL2 ( ortholog_one2one ) Macaque_ TSPYL2 ( ortholog_one2one ) Mouse_ Tspyl2 ( ortholog_one2one ) Pig_ TSPYL2 ( ortholog_one2one ) Rat_ Tspyl2 ( ortholog_one2one ) Rabbit_ TSPYL2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NAP1L4, NAP1L1, TSPYL6, TSPY9, TSPY2, TSPY8, TSPY3, TSPY4, TSPY10, TSPY1, NAP1L3, NAP1L2, SETSIP, NAP1L5, TSPYL5, TSPYL4, TSPYL1, SET |
| Tissue | amygdala, brain.meninx, caudate.nucleus, hippocampus, middle.frontal.gyrus, middle.temporal.gyrus, olfactory.apparatus, putamen |
| Tissue Specificity | Ubiquitously expressed, with highest levels in brain, testis and heart, and lowest levels in liver and pancreas. {ECO:0000269|PubMed:11149944, ECO:0000269|PubMed:11318608, ECO:0000269|PubMed:12393179, ECO:0000269|PubMed:15241014}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:11318608, ECO:0000269|PubMed:11395479}. Cytoplasm {ECO:0000250}. Note=Enriched in transcriptionally active regions of chromatin in neurons. {ECO:0000250}. |
| Mouse PG classification | NA |
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