Gene Information
Gene NameTSPO2
OrganismHomo sapiens (Human)
Gene Length170
Protein NamesTranslocator protein 2 (Peripheral-type benzodiazepine receptor-like protein 1)
Target NameNA
Target TypeNA
Gene Age645 ( ENSG00000112212 )
Evolutionary StageCellular_organisms
AlphaFoldDBQ5TGU0
Gene CardTSPO2
Uniprot IDQ5TGU0
PfamPF03073
In ASDno
Allosteric Predictionno (-0.944935217)
Ortholog in AnimalsAlpaca_ TSPO2 ( ortholog_one2one )
Dog_ TSPO2 ( ortholog_one2one )
GuineaPig_ TSPO2 ( ortholog_one2one )
Macaque_ TSPO2 ( ortholog_one2one )
Mouse_ Tspo2 ( ortholog_one2one )
Pig_ TSPO2 ( ortholog_one2one )
Rat_ Tspo2 ( ortholog_one2one )
Rabbit_ TSPO2 ( ortholog_one2one )
OhnologsNA
ParalogsTSPO
Tissuebone.marrow
Tissue SpecificityExpressed in erythrocytes (at protein level). {ECO:0000269|PubMed:27641616}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Endoplasmic reticulum membrane {ECO:0000269|PubMed:19729679};
Multi-pass membrane protein {ECO:0000269|PubMed:19729679}. Cell membrane {ECO:0000269|PubMed:27641616, ECO:0000269|PubMed:31989647};
Multi-pass membrane protein. Note=Localizes to the plasma membrane and intracellular membranes in developing and mature erythrocytes. {ECO:0000269|PubMed:27641616, ECO:0000269|PubMed:31989647}.
Mouse PG classificationNA
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