| Gene Information | |
|---|---|
| Gene Name | TSPAN8 |
| Organism | Homo sapiens (Human) |
| Gene Length | 237 |
| Protein Names | Tetraspanin-8 (Tspan-8) (Transmembrane 4 superfamily member 3) (Tumor-associated antigen CO-029) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000127324 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P19075 |
| Gene Card | TSPAN8 |
| Uniprot ID | P19075 |
| Pfam | PF00335 |
| In ASD | no |
| Allosteric Prediction | yes (0.351245751) |
| Ortholog in Animals | Alpaca_ TSPAN8 ( ortholog_one2one ) Dog_ TSPAN8 ( ortholog_one2one ) GuineaPig_ TSPAN8 ( ortholog_one2one ) Macaque_ TSPAN8 ( ortholog_one2one ) Mouse_ Tspan8 ( ortholog_one2one ) Rat_ Tspan8 ( ortholog_one2one ) Rabbit_ TSPAN8 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | ROM1, TSPAN12, CD63, TSPAN10, CD9, TSPAN6, TSPAN5, CD37, CD151, TSPAN4, TSPAN1, TSPAN31, UPK1A, TSPAN17, TSPAN11, TSPAN32, TSPAN13, TSPAN2, CD53, TSPAN9, TSPAN18, CD81, CD82, TSPAN16, TSPAN19, TSPAN7, UPK1B, TSPAN3, TSPAN14, TSPAN15, PRPH2, TSPAN33 |
| Tissue | NA |
| Tissue Specificity | Gastric, colon, rectal, and pancreatic carcinomas. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs17849952 rs3763978 rs1051334 |
| Subcellular location [CC] | Membrane; Multi-pass membrane protein. |
| Mouse PG classification | NA |
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