| Gene Information | |
|---|---|
| Gene Name | MCT4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 465 |
| Protein Names | Monocarboxylate transporter 4 (MCT 4) (Solute carrier family 16 member 3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | O15427 |
| Gene Card | SLC16A3 |
| Uniprot ID | O15427 |
| Pfam | PF07690 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Highly expressed in skeletal muscle. {ECO:0000269|PubMed:9425115}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:10921872, ECO:0000269|PubMed:11101640, ECO:0000269|PubMed:15505343, ECO:0000269|PubMed:23935841}; Multi-pass membrane protein. Basolateral cell membrane {ECO:0000269|PubMed:21199217}; Multi-pass membrane protein {ECO:0000255}. Note=Plasma membrane localization is dependent upon the BSG/MCT4 interaction (PubMed:10921872). Basolateral sorting signals (BLSS) in C-terminal cytoplasmic tail ensure its basolateral expression in polarised epithelial cells (PubMed:21199217). {ECO:0000269|PubMed:10921872, ECO:0000269|PubMed:21199217}. |
| Mouse PG classification | NA |
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