| Gene Information | |
|---|---|
| Gene Name | NIBAN1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 928 |
| Protein Names | Protein Niban 1 (Cell growth-inhibiting gene 39 protein) (Protein FAM129A) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000135842 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q9BZQ8 |
| Gene Card | NIBAN1 |
| Uniprot ID | Q9BZQ8 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-0.88539224) |
| Ortholog in Animals | Alpaca_ NIBAN1 ( ortholog_one2one ) Dog_ NIBAN1 ( ortholog_one2one ) Macaque_ NIBAN1 ( ortholog_one2one ) Mouse_ Niban1 ( ortholog_one2one ) Pig_ NIBAN1 ( ortholog_one2one ) Rat_ Niban1 ( ortholog_one2one ) Rabbit_ NIBAN1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NIBAN3, NIBAN2 |
| Tissue | NA |
| Tissue Specificity | Expressed in various types of thyroid tumor such as papillary thyroid carcinomas and oxyphilic thyroid tumors but not in normal thyroid tissue (at protein level). Strongly expressed in heart, skeletal muscle, pancreas, white blood cells and prostate with moderate expression in colon and spleen. Expressed in renal carcinoma cells but not in normal kidney. {ECO:0000269|PubMed:11011112, ECO:0000269|PubMed:16949643}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs12750174 rs35704242 rs17313374 rs35601690 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:16949643}. Membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}. |
| Mouse PG classification | NA |
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