Gene Information
Gene NameTSKS
OrganismHomo sapiens (Human)
Gene Length592
Protein NamesTestis-specific serine kinase substrate (Testis-specific kinase substrate) (STK22 substrate 1)
Target NameNA
Target TypeNA
Gene Age132 ( ENSG00000126467 )
Evolutionary StageMammalia
AlphaFoldDBQ9UJT2
Gene CardTSKS
Uniprot IDQ9UJT2
PfamPF15358
In ASDno
Allosteric Predictionno (-0.676898885)
Ortholog in AnimalsAlpaca_ TSKS ( ortholog_one2one )
Dog_ TSKS ( ortholog_one2one )
GuineaPig_ TSKS ( ortholog_one2one )
Macaque_ TSKS ( ortholog_one2one )
Mouse_ Tsks ( ortholog_one2one )
Pig_ TSKS ( ortholog_one2one )
Rat_ Tsks ( ortholog_one2one )
Rabbit_ TSKS ( ortholog_one2one )
OhnologsNA
ParalogsNA
Tissuetestis
Tissue SpecificityHighly expressed in testis. Expressed at low levels in prostate, female breast, placenta, ovary and thymus. {ECO:0000269|PubMed:11444856, ECO:0000269|PubMed:15044604}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs149529240  rs34701020  rs2304202 
Subcellular location [CC]Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000269|PubMed:18495105}. Note=Concentrates in spermatid centrioles during flagellogenesis.
Mouse PG classificationNA
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