| Gene Information | |
|---|---|
| Gene Name | BPGM |
| Organism | Homo sapiens (Human) |
| Gene Length | 259 |
| Protein Names | Bisphosphoglycerate mutase (BPGM) (EC 5.4.2.4) (2,3-bisphosphoglycerate mutase, erythrocyte) (2,3-bisphosphoglycerate synthase) (EC 5.4.2.11) (2,3-diphosphoglycerate mutase) (DPGM) (BPG-dependent PGAM) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000172331 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | P07738 |
| Gene Card | BPGM |
| Uniprot ID | P07738 |
| Pfam | PF00300 |
| In ASD | yes |
| Allosteric Prediction | no (-0.437044221) |
| Ortholog in Animals | Alpaca_ BPGM ( ortholog_one2one ) Dog_ BPGM ( ortholog_one2one ) GuineaPig_ BPGM ( ortholog_one2one ) Macaque_ BPGM ( ortholog_one2one ) Mouse_ Bpgm ( ortholog_one2one ) Pig_ BPGM ( ortholog_one2one ) Rat_ Bpgm ( ortholog_one2one ) Rabbit_ BPGM ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | PGAM1, PGAM2, PGAM4 |
| Tissue | NA |
| Tissue Specificity | Expressed in red blood cells. Expressed in non-erythroid cells of the placenta; present in the syncytiotrophoblast layer of the placental villi at the feto-maternal interface (at protein level). {ECO:0000269|PubMed:16246416, ECO:0000269|PubMed:3023066, ECO:0000269|PubMed:6313356}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1T8P (X-ray 2.50A ) 2A9J (X-ray 2.00A ) 2F90 (X-ray 2.00A ) 2H4X (X-ray 1.85A ) 2H4Z (X-ray 2.00A ) 2H52 (X-ray 2.00A ) 2HHJ (X-ray 1.50A ) 3NFY (X-ray 1.94A ) 7N3R (X-ray 2.25A ) 7N3S (X-ray 2.48A ) 7THI (X-ray 1.33A ) |
| DBSNP | rs751972865 rs121964925 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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