Gene Information
Gene NameTSH3
OrganismHomo sapiens (Human)
Gene Length1081
Protein NamesTeashirt homolog 3 (Zinc finger protein 537)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBQ63HK5
Gene CardTSHZ3
Uniprot IDQ63HK5
PfamNA
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityExpressed in brain;
strongly reduced in post-mortem elderly subjects with Alzheimer disease (PubMed:18776146, PubMed:19343227). Expressed in the fetal neocortex (PubMed:27668656). {ECO:0000269|PubMed:18776146, ECO:0000269|PubMed:19343227, ECO:0000269|PubMed:27668656}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 2DMI  (NMR 
DBSNP rs143453460  rs4805664 
Subcellular location [CC]Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108, ECO:0000269|PubMed:19343227}. Cell projection, growth cone {ECO:0000250}. Note=Colocalizes with APBB1 in axonal growth cone (By similarity). Colocalizes with APBB1 in the nucleus. {ECO:0000250}.
Mouse PG classificationNA
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