| Gene Information | |
|---|---|
| Gene Name | TSG6 |
| Organism | Homo sapiens (Human) |
| Gene Length | 277 |
| Protein Names | Tumor necrosis factor-inducible gene 6 protein (EC 3.1.1.-) (Hyaluronate-binding protein) (TNF-stimulated gene 6 protein) (TSG-6) (Tumor necrosis factor alpha-induced protein 6) (TNF alpha-induced protein 6) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P98066 |
| Gene Card | TNFAIP6 |
| Uniprot ID | P98066 |
| Pfam | PF00431; PF00193 |
| In ASD | yes |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in airway epithelium and submucosal gland (at protein level). Colocalizes with bikunin at the ciliary border. Present in bronchoalveolar lavage fluid (at protein level) (PubMed:16873769). Expressed in mesenchymal stem cells (PubMed:16771708). Found in the synovial fluid of patients with rheumatoid arthritis. {ECO:0000269|PubMed:16771708, ECO:0000269|PubMed:16873769, ECO:0000269|PubMed:7516184}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | 1O7B (NMR - ) 1O7C (NMR - ) 2N40 (NMR - ) 2PF5 (X-ray 1.90A ) 2WNO (X-ray 2.30A ) |
| DBSNP | rs1046668 |
| Subcellular location [CC] | Secreted {ECO:0000269|PubMed:1730767}. |
| Mouse PG classification | NA |
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