| Gene Information | |
|---|---|
| Gene Name | TSEN15 |
| Organism | Homo sapiens (Human) |
| Gene Length | 171 |
| Protein Names | tRNA-splicing endonuclease subunit Sen15 (SEN15 homolog) (HsSEN15) (tRNA-intron endonuclease Sen15) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000198860 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q8WW01 |
| Gene Card | TSEN15 |
| Uniprot ID | Q8WW01 |
| Pfam | PF09631 |
| In ASD | no |
| Allosteric Prediction | no (-1.800383206) |
| Ortholog in Animals | Alpaca_ TSEN15 ( ortholog_one2one ) Dog_ TSEN15 ( ortholog_one2one ) GuineaPig_ TSEN15 ( ortholog_one2one ) Macaque_ TSEN15 ( ortholog_one2one ) Mouse_ Tsen15 ( ortholog_one2one ) Pig_ TSEN15 ( ortholog_one2one ) Rat_ Tsen15 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Widely expressed. Highly expressed in testis and uterus. {ECO:0000269|PubMed:11318611}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2GW6 (NMR - ) 6Z9U (X-ray 2.10A ) |
| DBSNP | rs2274432 rs1046934 rs730882223 rs879253780 rs879253779 |
| Subcellular location [CC] | Nucleus {ECO:0000305}. Nucleus, nucleolus {ECO:0000305}. Note=May be transiently localized in the nucleolus. {ECO:0000305}. |
| Mouse PG classification | NA |
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