| Gene Information | |
|---|---|
| Gene Name | CLN5 |
| Organism | Homo sapiens (Human) |
| Gene Length | 358 |
| Protein Names | Ceroid-lipofuscinosis neuronal protein 5 (Protein CLN5) [Cleaved into: Ceroid-lipofuscinosis neuronal protein 5, secreted form] |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000102805 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O75503 |
| Gene Card | CLN5 |
| Uniprot ID | O75503 |
| Pfam | PF15014 |
| In ASD | no |
| Allosteric Prediction | no (-0.23737565) |
| Ortholog in Animals | Alpaca_ CLN5 ( ortholog_one2one ) Dog_ CLN5 ( ortholog_one2one ) GuineaPig_ CLN5 ( ortholog_one2one ) Macaque_ CLN5 ( ortholog_one2one ) Mouse_ Cln5 ( ortholog_one2one ) Pig_ CLN5 ( ortholog_one2one ) Rat_ AABR07008608.1 ( ortholog_one2many ) Rat_ Cln5 ( ortholog_one2many ) Rabbit_ CLN5 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs199727787 rs104894386 rs104894386 rs267606738 rs386833975 rs386833976 rs386833977 rs147065248 rs386833978 rs138611001 rs386833981 rs11842935 rs28940280 rs1800209 rs148862100 rs386833968 |
| Subcellular location [CC] | [Ceroid-lipofuscinosis neuronal protein 5, secreted form]: Lysosome {ECO:0000269|PubMed:11971870, ECO:0000269|PubMed:20052765, ECO:0000269|PubMed:22431521, ECO:0000269|PubMed:24038957, ECO:0000269|PubMed:24058541}.; [Ceroid-lipofuscinosis neuronal protein 5]: Membrane {ECO:0000269|PubMed:24038957}; Single-pass type II membrane protein {ECO:0000269|PubMed:24038957}. Note=An amphipathic anchor region facilitates its association with the membrane. {ECO:0000269|PubMed:24038957}. |
| Mouse PG classification | NA |
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