| Gene Information | |
|---|---|
| Gene Name | PPP1R12C |
| Organism | Homo sapiens (Human) |
| Gene Length | 782 |
| Protein Names | Protein phosphatase 1 regulatory subunit 12C (Protein phosphatase 1 myosin-binding subunit of 85 kDa) (Protein phosphatase 1 myosin-binding subunit p85) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000125503 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9BZL4 |
| Gene Card | PPP1R12C |
| Uniprot ID | Q9BZL4 |
| Pfam | PF12796; PF15898 |
| In ASD | no |
| Allosteric Prediction | no (-0.880941935) |
| Ortholog in Animals | Alpaca_ PPP1R12C ( ortholog_one2one ) Dog_ PPP1R12C ( ortholog_one2one ) GuineaPig_ PPP1R12C ( ortholog_one2one ) Macaque_ PPP1R12C ( ortholog_one2one ) Mouse_ Ppp1r12c ( ortholog_one2one ) Pig_ PPP1R12C ( ortholog_one2one ) Rat_ Ppp1r12c ( ortholog_one2one ) |
| Ohnologs | PPP1R12A, PPP1R12B |
| Paralogs | PPP1R12A, PPP1R27, PPP1R12B |
| Tissue | NA |
| Tissue Specificity | Ubiquitously expressed. Highly expressed in heart. {ECO:0000269|PubMed:11399775}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs35849605 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:11399775, ECO:0000269|PubMed:12923170}. Cytoplasm, cytoskeleton, stress fiber {ECO:0000269|PubMed:11399775, ECO:0000269|PubMed:12923170}. |
| Mouse PG classification | NA |
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