| Gene Information | |
|---|---|
| Gene Name | QRFPR |
| Organism | Homo sapiens (Human) |
| Gene Length | 431 |
| Protein Names | Pyroglutamylated RF-amide peptide receptor (AQ27) (G-protein coupled receptor 103) (Orexigenic neuropeptide QRFP receptor) (SP9155) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000186867 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q96P65 |
| Gene Card | QRFPR |
| Uniprot ID | Q96P65 |
| Pfam | PF00001 |
| In ASD | no |
| Allosteric Prediction | yes (0.081839055) |
| Ortholog in Animals | Alpaca_ QRFPR ( ortholog_one2one ) Dog_ QRFPR ( ortholog_one2one ) GuineaPig_ QRFPR ( ortholog_one2one ) Macaque_ QRFPR ( ortholog_one2one ) Mouse_ Qrfpr ( ortholog_one2many ) Mouse_ Qrfprl ( ortholog_one2many ) Pig_ QRFPR ( ortholog_one2one ) Rat_ Qrfpr ( ortholog_one2many ) Rat_ RGD1560028 ( ortholog_one2many ) Rabbit_ QRFPR ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | OXTR, AVPR2, AVPR1B, AVPR1A, GNRHR, GALR3, GPR22, GPR150, FFAR4, GALR1, NPFFR1, HCRTR2, HCRTR1, NPFFR2, CCKBR, CCKAR |
| Tissue | NA |
| Tissue Specificity | Expressed widely in the brain with high levels in the hypothalamus, trigeminal ganglia and vestibular neurons, and moderate levels in the amygdala, cortex, pituitary, hippocampus, thalamus, caudate nucleus and medulla oblongata. In peripheral tissues, expressed at high levels in the retina and at moderate levels in the heart, kidney, testis and thyroid. {ECO:0000269|PubMed:11574155, ECO:0000269|PubMed:12714592}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | rs17438900 rs11947418 rs2302310 |
| Subcellular location [CC] | Cell membrane; Multi-pass membrane protein. |
| Mouse PG classification | NA |
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