| Gene Information | |
|---|---|
| Gene Name | TRO |
| Organism | Homo sapiens (Human) |
| Gene Length | 1431 |
| Protein Names | Trophinin (MAGE-D3 antigen) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000067445 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q12816 |
| Gene Card | TRO |
| Uniprot ID | Q12816 |
| Pfam | PF01454 |
| In ASD | no |
| Allosteric Prediction | no (-0.937223559) |
| Ortholog in Animals | Alpaca_ TRO ( ortholog_one2one ) Macaque_ TRO ( ortholog_one2one ) Mouse_ Tro ( ortholog_one2one ) Pig_ TRO ( ortholog_one2one ) Rabbit_ TRO ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | MAGED4, MAGED4B, MAGEB17, MAGEB1, MAGEA3, MAGEA6, MAGEL2, MAGEA2, MAGEA2B, MAGEA12, NDN, MAGEB6, MAGEB6B, MAGEB2, MAGEH1, MAGEA8, MAGEE2, MAGEA11, MAGEB5, MAGED1, MAGEB10, MAGEA10, MAGEA4, MAGEB4, MAGEC3, MAGEE1, MAGEA9, MAGEA9B, MAGEB3, MAGEC1, MAGEC2, NSMCE3, MAGEA1, MAGEB18, MAGEB16, MAGEF1, MAGED2 |
| Tissue | NA |
| Tissue Specificity | Strong expression at implantation sites. Found in the placenta from the sixth week of pregnancy. Was localized in the cytoplasm of the syncytiotrophoblast in the chorionic villi and in endometrial decidual cells at the uteroplacental interface. After week 10, the level decreased and then disappeared from placental villi. Also found in macrophages. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs60674633 rs17297490 rs1211752617 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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