| Gene Information | |
|---|---|
| Gene Name | TRMU |
| Organism | Homo sapiens (Human) |
| Gene Length | 421 |
| Protein Names | Mitochondrial tRNA-specific 2-thiouridylase 1 (EC 2.8.1.14) (MTO2 homolog) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000100416 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | O75648 |
| Gene Card | TRMU |
| Uniprot ID | O75648 |
| Pfam | PF20258; PF20259 |
| In ASD | no |
| Allosteric Prediction | no (-1.459243223) |
| Ortholog in Animals | Alpaca_ TRMU ( ortholog_one2one ) Dog_ TRMU ( ortholog_one2one ) GuineaPig_ TRMU ( ortholog_one2one ) Macaque_ TRMU ( ortholog_one2one ) Mouse_ Trmu ( ortholog_one2one ) Pig_ TRMU ( ortholog_one2one ) Rat_ Trmu ( ortholog_one2one ) Rabbit_ TRMU ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. Abundantly expressed in tissues with high metabolic rates including heart, liver, kidney, and brain. {ECO:0000269|PubMed:16513084}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs11090865 rs751248771 rs2272938 rs118203990 rs34012206 rs118203991 rs387907022 rs34152016 |
| Subcellular location [CC] | Mitochondrion {ECO:0000269|PubMed:15509579, ECO:0000269|PubMed:15944150, ECO:0000269|PubMed:16513084, ECO:0000269|PubMed:16826519}. |
| Mouse PG classification | NA |
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