Gene Information
Gene NameTRMT6
OrganismHomo sapiens (Human)
Gene Length497
Protein NamestRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 (mRNA methyladenosine-N(1)-methyltransferase non-catalytic subunit TRM6) (tRNA(m1A58)-methyltransferase subunit TRM6) (tRNA(m1A58)MTase subunit TRM6)
Target NameNA
Target TypeNA
Gene Age987 ( ENSG00000089195 )
Evolutionary StageEukaryota
AlphaFoldDBQ9UJA5
Gene CardTRMT6
Uniprot IDQ9UJA5
PfamPF04189
In ASDno
Allosteric Predictionno (-1.556969928)
Ortholog in AnimalsAlpaca_ TRMT6 ( ortholog_one2one )
Dog_ TRMT6 ( ortholog_one2one )
GuineaPig_ TRMT6 ( ortholog_one2one )
Macaque_ TRMT6 ( ortholog_one2one )
Mouse_ Trmt6 ( ortholog_one2one )
Pig_ TRMT6 ( ortholog_one2one )
Rat_ Trmt6 ( ortholog_one2one )
Rabbit_ TRMT6 ( ortholog_one2one )
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityExpressed in brain, liver, testis and ovary. {ECO:0000269|PubMed:10574461}.
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);0.004740(Rat);0.075000(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 5CCB  (X-ray  2.00A  5CCX  (X-ray  2.10A  5CD1  (X-ray  3.60A 
DBSNP rs6139876  rs451571  rs35203742 
Subcellular location [CC]Nucleus {ECO:0000250|UniProtKB:P41814}.
Mouse PG classificationNA
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