| Gene Information | |
|---|---|
| Gene Name | TRMT2A |
| Organism | Homo sapiens (Human) |
| Gene Length | 625 |
| Protein Names | tRNA (uracil-5-)-methyltransferase homolog A (EC 2.1.1.35) (mRNA (uracil-5-)-methyltransferase TRMT2A) (EC 2.1.1.-) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000099899 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q8IZ69 |
| Gene Card | TRMT2A |
| Uniprot ID | Q8IZ69 |
| Pfam | PF05958 |
| In ASD | no |
| Allosteric Prediction | no (-1.217044345) |
| Ortholog in Animals | Alpaca_ TRMT2A ( ortholog_one2one ) Dog_ TRMT2A ( ortholog_one2one ) GuineaPig_ TRMT2A ( ortholog_one2one ) Macaque_ TRMT2A ( ortholog_one2one ) Mouse_ Trmt2a ( ortholog_one2one ) Pig_ TRMT2A ( ortholog_one2one ) Rat_ Trmt2a ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | TRMT2B |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7NTN (X-ray 2.02A ) 7NTO (X-ray 1.23A ) |
| DBSNP | rs447017 |
| Subcellular location [CC] | Cytoplasm, cytosol {ECO:0000305|PubMed:31361898}. |
| Mouse PG classification | NA |
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