| Gene Information | |
|---|---|
| Gene Name | TRMT112 |
| Organism | Homo sapiens (Human) |
| Gene Length | 125 |
| Protein Names | Multifunctional methyltransferase subunit TRM112-like protein (tRNA methyltransferase 112 homolog) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 168 ( ENSG00000173113 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9UI30 |
| Gene Card | TRMT112 |
| Uniprot ID | Q9UI30 |
| Pfam | PF03966 |
| In ASD | no |
| Allosteric Prediction | no (-1.680007549) |
| Ortholog in Animals | Alpaca_ TRMT112 ( ortholog_one2one ) Dog_ TRMT112 ( ortholog_one2one ) GuineaPig_ TRMT112 ( ortholog_one2one ) Macaque_ TRMT112 ( ortholog_one2one ) Mouse_ Trmt112 ( ortholog_one2one ) Pig_ TRMT112 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.011321(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6G4W (EM 4.50A ) 6H1D (X-ray 1.94A ) 6H1E (X-ray 1.90A ) 6H2U (X-ray 1.60A ) 6H2V (X-ray 2.49A ) 6K0X (X-ray 2.20A ) 6KHS (X-ray 1.90A ) 6KMR (X-ray 2.00A ) 6KMS (X-ray 3.20A ) 6PED (X-ray 2.30A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus, nucleoplasm {ECO:0000269|PubMed:25851604}. Cytoplasm, perinuclear region {ECO:0000269|PubMed:25851604}. Note=Localizes to a polarized perinuclear structure, overlapping partially with the Golgi and lysosomes (PubMed:25851604). {ECO:0000269|PubMed:25851604}. |
| Mouse PG classification | NA |
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