| Gene Information | |
|---|---|
| Gene Name | CDC42EP3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 254 |
| Protein Names | Cdc42 effector protein 3 (Binder of Rho GTPases 2) (MSE55-related Cdc42-binding protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000163171 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q9UKI2 |
| Gene Card | CDC42EP3 |
| Uniprot ID | Q9UKI2 |
| Pfam | PF14957; PF00786 |
| In ASD | no |
| Allosteric Prediction | no (-1.453078391) |
| Ortholog in Animals | Alpaca_ CDC42EP3 ( ortholog_one2one ) Dog_ CDC42EP3 ( ortholog_one2one ) GuineaPig_ CDC42EP3 ( ortholog_one2one ) Macaque_ CDC42EP3 ( ortholog_one2one ) Mouse_ Cdc42ep3 ( ortholog_one2one ) Pig_ CDC42EP3 ( ortholog_one2one ) Rat_ Cdc42ep3 ( ortholog_one2one ) Rabbit_ CDC42EP3 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CDC42EP5, C15orf62, CDC42EP1, CDC42EP2, CDC42EP4 |
| Tissue | testis |
| Tissue Specificity | Highly expressed in the heart and weakly in the brain. {ECO:0000269|PubMed:10490598}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Endomembrane system {ECO:0000269|PubMed:11035016}; Peripheral membrane protein {ECO:0000269|PubMed:11035016}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:11035016}. |
| Mouse PG classification | NA |
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