| Gene Information | |
|---|---|
| Gene Name | SOX13 |
| Organism | Homo sapiens (Human) |
| Gene Length | 622 |
| Protein Names | Transcription factor SOX-13 (Islet cell antigen 12) (SRY (Sex determining region Y)-box 13) (Type 1 diabetes autoantigen ICA12) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1714 ( ENSG00000143842 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9UN79 |
| Gene Card | SOX13 |
| Uniprot ID | Q9UN79 |
| Pfam | PF00505 |
| In ASD | no |
| Allosteric Prediction | no (-1.429965514) |
| Ortholog in Animals | Alpaca_ SOX13 ( ortholog_one2one ) Dog_ SOX13 ( ortholog_one2one ) GuineaPig_ SOX13 ( ortholog_one2one ) Macaque_ SOX13 ( ortholog_one2one ) Mouse_ Sox13 ( ortholog_one2one ) Pig_ SOX13 ( ortholog_one2one ) Rat_ Sox13 ( ortholog_one2one ) Rabbit_ SOX13 ( ortholog_one2one ) |
| Ohnologs | SOX6, SOX5 |
| Paralogs | SOX12, SOX17, SOX30, CFAP65, SOX21, SOX8, SOX7, SOX5, SOX14, SOX6, SOX9, SRY, SOX10, SOX1, SOX4, SOX18, SOX11, SOX3, SOX2, SOX15 |
| Tissue | NA |
| Tissue Specificity | Expressed in exocrine cells and islets of Langerhans in the pancreas (at protein level) (PubMed:10871192). Expressed in the pancreas, placenta, kidney, brain, heart, lung, and liver (PubMed:10871192, PubMed:20028982). Expressed in adipose tissue, cervix, colon, esophagus, ovary, prostate, small intestine, spleen, testicle, thymus and thyroid (PubMed:20028982). {ECO:0000269|PubMed:10871192, ECO:0000269|PubMed:20028982}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs34758764 |
| Subcellular location [CC] | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00267}. Cytoplasm {ECO:0000269|PubMed:10871192}. |
| Mouse PG classification | NA |
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