| Gene Information | |
|---|---|
| Gene Name | SOX11 |
| Organism | Homo sapiens (Human) |
| Gene Length | 441 |
| Protein Names | Transcription factor SOX-11 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1714 ( ENSG00000176887 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P35716 |
| Gene Card | SOX11 |
| Uniprot ID | P35716 |
| Pfam | PF00505 |
| In ASD | no |
| Allosteric Prediction | no (-0.267432262) |
| Ortholog in Animals | Alpaca_ SOX11 ( ortholog_one2one ) Dog_ SOX11 ( ortholog_one2one ) GuineaPig_ SOX11 ( ortholog_one2one ) Macaque_ SOX11 ( ortholog_one2one ) Mouse_ Sox11 ( ortholog_one2one ) Pig_ SOX11 ( ortholog_one2one ) Rat_ Sox11 ( ortholog_one2one ) Rabbit_ SOX11 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | SOX12, SOX17, SOX13, SOX30, CFAP65, SOX21, SOX8, SOX7, SOX5, SOX14, SOX6, SOX9, SRY, SOX10, SOX1, SOX4, SOX18, SOX3, SOX2, SOX15 |
| Tissue | brain |
| Tissue Specificity | Expressed primarily in the brain and heart, with low expression in the kidney, pancreas and muscle. {ECO:0000269|PubMed:24886874}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6T78 (X-ray 2.50A ) 6T7A (EM 3.70A ) 6T7C (EM 4.00A ) 6T7D (EM 4.40A ) |
| DBSNP | rs587777480 rs587777479 |
| Subcellular location [CC] | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00267, ECO:0000269|PubMed:24886874}. |
| Mouse PG classification | NA |
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