| Gene Information | |
|---|---|
| Gene Name | TRIM69 |
| Organism | Homo sapiens (Human) |
| Gene Length | 500 |
| Protein Names | E3 ubiquitin-protein ligase TRIM69 (EC 2.3.2.27) (RFP-like domain-containing protein trimless) (RING finger protein 36) (RING-type E3 ubiquitin transferase TRIM69) (Tripartite motif-containing protein 69) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 382 ( ENSG00000185880 ) 3 ( ENSG00000278211 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q86WT6 |
| Gene Card | TRIM69 |
| Uniprot ID | Q86WT6 |
| Pfam | PF13765; PF00622 |
| In ASD | no |
| Allosteric Prediction | no (-0.907883175) |
| Ortholog in Animals | Alpaca_ TRIM69 ( ortholog_one2one ) Dog_ TRIM69 ( ortholog_one2one ) GuineaPig_ TRIM69 ( ortholog_one2one ) Macaque_ TRIM69 ( ortholog_one2one ) Mouse_ Trim69 ( ortholog_one2one ) Pig_ TRIM69 ( ortholog_one2one ) Rat_ Trim69 ( ortholog_one2one ) Rabbit_ TRIM69 ( ortholog_one2one ) |
| Ohnologs | TRIM58, TRIM17 |
| Paralogs | TRIM42, TRIM13, TRIM31, TRIM49B, TRIM49C, TRIM49, TRIM33, TRIM71, TRIM77, TRIM28, TRIM3, TRIM46, TRIM58, TRIM38, TRIM5, TRIM37, MID1, TRIM7, TRIM36, TRIM44, TRIML2, TRIM2, TRIM63, TRIM73, TRIM74, TRIM65, TRIML1, MID2, TRIM32, TRIM14, TRIM34, TRIM54, TRIM55, TRIM52, TRIM41, TRIM11, PML, TRIM43, TRIM43B, TRIM21, TRIM6, TRIM27, TRIM40, TRIM51G, TRIM51, TRIM9, TRIM67, TRIM25, TRIM49D1, TRIM48, TRIM49D2, TRIM68, TRIM17, TRIM24, TRIM64C, TRIM64, TRIM64B, TRIM60, TRIM61, TRIM4, TRIM10, BSPRY, TRIM56, TRIM29, TRIM8, MEFV, TRIM15, TRIM22, TRIM35, TRIM16, TRIM47, TRIM45, TRIM72, TRIM62, TRIM50, TRIM75, TRIM66, RNF39, TRIM26, TRIM39 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.025(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4NQJ (X-ray 2.15A ) 6YXE (X-ray 2.10A ) |
| DBSNP | rs2444007 rs2470911 rs3759880 rs17588988 rs3100139 rs3759880 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:23131556, ECO:0000269|PubMed:31578292}. Nucleus {ECO:0000269|PubMed:23131556}. Nucleus speckle {ECO:0000269|PubMed:23131556}. |
| Mouse PG classification | NA |
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