| Gene Information | |
|---|---|
| Gene Name | RND2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 227 |
| Protein Names | Rho-related GTP-binding protein RhoN (Rho family GTPase 2) (Rho-related GTP-binding protein Rho7) (Rnd2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000108830 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P52198 |
| Gene Card | RND2 |
| Uniprot ID | P52198 |
| Pfam | PF00071 |
| In ASD | no |
| Allosteric Prediction | no (-0.950819349) |
| Ortholog in Animals | Alpaca_ RND2 ( ortholog_one2one ) Dog_ RND2 ( ortholog_one2one ) GuineaPig_ RND2 ( ortholog_one2one ) Macaque_ RND2 ( ortholog_one2one ) Mouse_ Rnd2 ( ortholog_one2one ) Pig_ RND2 ( ortholog_one2one ) Rat_ Rnd2 ( ortholog_one2one ) Rabbit_ RND2 ( ortholog_one2one ) |
| Ohnologs | RND3, RND1 |
| Paralogs | RND1, CDC42, RHOT1, RHOBTB3, RHOT2, RAC1, RAC3, RHOJ, RHOA, RHOC, RHOB, RHOV, RHOQ, RHOBTB2, RND3, RHOD, RHOF, RHOG, RHOU, RAC2, RHOBTB1, RHOH |
| Tissue | testis, brain, liver |
| Tissue Specificity | Highly expressed in testis. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.004323(Rat);0.05(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasmic vesicle, secretory vesicle, acrosome membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}. Note=Colocalizes with RACGAP1 in Golgi-derived proacrosomal vesicles and the acrosome. {ECO:0000269|PubMed:12590651}. |
| Mouse PG classification | NA |
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