Gene Information
Gene NamePDYN
OrganismHomo sapiens (Human)
Gene Length254
Protein NamesProenkephalin-B (Beta-neoendorphin-dynorphin) (Preprodynorphin) [Cleaved into: Alpha-neoendorphin; Beta-neoendorphin; Big dynorphin (Big Dyn); Dynorphin A(1-17) (Dyn-A17) (Dynorphin A); Dynorphin A(1-13); Dynorphin A(1-8); Leu-enkephalin; Rimorphin (Dynorphin B) (Dyn-B) (Dynorphin B(1-13)); Leumorphin (Dynorphin B-29)]
Target NameNA
Target TypeNA
Gene Age544 ( ENSG00000101327 )
Evolutionary StageVertebrata
AlphaFoldDBP01213
Gene CardPDYN
Uniprot IDP01213
PfamPF01160
In ASDno
Allosteric Predictionyes (0.531437977)
Ortholog in AnimalsAlpaca_ PDYN ( ortholog_one2one )
Dog_ PDYN ( ortholog_one2one )
GuineaPig_ PDYN ( ortholog_one2one )
Macaque_ PDYN ( ortholog_one2one )
Mouse_ Pdyn ( ortholog_one2one )
Pig_ PDYN ( ortholog_one2one )
Rat_ Pdyn ( ortholog_one2one )
Rabbit_ PDYN ( ortholog_one2one )
OhnologsNA
ParalogsPENK, PNOC
Tissuebrain, cerebral.cortex, putamen, nucleus.accumbens
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 2N2F  (NMR 
DBSNP rs773876922  rs369559888  rs267606941  rs575606358  rs1004881058  rs267606940  rs201486601  rs267606939 
Subcellular location [CC]Secreted.
Mouse PG classificationNA
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