| Gene Information | |
|---|---|
| Gene Name | SAMD4A |
| Organism | Homo sapiens (Human) |
| Gene Length | 718 |
| Protein Names | Protein Smaug homolog 1 (Smaug 1) (hSmaug1) (Sterile alpha motif domain-containing protein 4A) (SAM domain-containing protein 4A) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1292 ( ENSG00000020577 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9UPU9 |
| Gene Card | SAMD4A |
| Uniprot ID | Q9UPU9 |
| Pfam | PF00536 |
| In ASD | no |
| Allosteric Prediction | no (-0.326155637) |
| Ortholog in Animals | Alpaca_ SAMD4A ( ortholog_one2one ) Dog_ SAMD4A ( ortholog_one2one ) GuineaPig_ SAMD4A ( ortholog_one2one ) Macaque_ SAMD4A ( ortholog_one2one ) Mouse_ Samd4 ( ortholog_one2one ) Pig_ SAMD4A ( ortholog_one2one ) Rat_ Samd4a ( ortholog_one2one ) Rabbit_ SAMD4A ( ortholog_one2one ) |
| Ohnologs | SAMD4B |
| Paralogs | SAMD4B |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:16221671}. Cell projection, dendrite {ECO:0000250}. Synapse, synaptosome {ECO:0000250}. Note=Enriched in synaptoneurosomes (By similarity). Shuttles between the nucleus and the cytoplasm in a CRM1-dependent manner. Colocalizes throughout the cytoplasm in granules with polyadenylated RNAs, PABPC1 and STAU1. Also frequently colocalizes in cytoplasmic stress granule-like foci with ELAVL1, TIA1 and TIAL1. {ECO:0000250}. |
| Mouse PG classification | NA |
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