| Gene Information | |
|---|---|
| Gene Name | TRIM3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 744 |
| Protein Names | Tripartite motif-containing protein 3 (Brain-expressed RING finger protein) (RING finger protein 22) (RING finger protein 97) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000110171 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | O75382 |
| Gene Card | TRIM3 |
| Uniprot ID | O75382 |
| Pfam | PF00630; PF01436; PF00643; PF13445 |
| In ASD | no |
| Allosteric Prediction | no (-1.035295024) |
| Ortholog in Animals | Alpaca_ TRIM3 ( ortholog_one2one ) Dog_ TRIM3 ( ortholog_one2one ) GuineaPig_ TRIM3 ( ortholog_one2one ) Macaque_ TRIM3 ( ortholog_one2one ) Mouse_ Trim3 ( ortholog_one2one ) Pig_ TRIM3 ( ortholog_one2one ) Rat_ Trim3 ( ortholog_one2one ) Rabbit_ TRIM3 ( ortholog_one2one ) |
| Ohnologs | TRIM2 |
| Paralogs | TRIM42, TRIM13, TRIM31, TRIM49B, TRIM49C, TRIM49, TRIM33, TRIM69, TRIM71, TRIM77, TRIM28, TRIM46, TRIM58, TRIM38, TRIM5, TRIM37, MID1, TRIM7, TRIM36, TRIM44, TRIML2, TRIM2, TRIM63, TRIM73, TRIM74, TRIM65, TRIML1, MID2, TRIM32, TRIM14, TRIM34, TRIM54, TRIM55, TRIM52, TRIM41, TRIM11, PML, TRIM43, TRIM43B, TRIM21, TRIM6, TRIM27, TRIM40, TRIM51G, TRIM51, TRIM9, TRIM67, TRIM25, TRIM49D1, TRIM48, TRIM49D2, TRIM68, TRIM17, TRIM24, TRIM64C, TRIM64, TRIM64B, TRIM60, TRIM61, TRIM4, TRIM10, BSPRY, TRIM56, TRIM29, TRIM8, MEFV, TRIM15, TRIM22, TRIM35, TRIM16, TRIM47, TRIM45, TRIM72, TRIM62, TRIM50, TRIM75, TRIM66, RNF39, TRIM26, TRIM39 |
| Tissue | small.intestine |
| Tissue Specificity | Expressed in brain, heart, uterus and testis. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7O0B (X-ray 2.13A ) 7QRW (X-ray 1.70A ) |
| DBSNP | rs10128723 |
| Subcellular location [CC] | Cytoplasm {ECO:0000250}. Early endosome {ECO:0000269|PubMed:15772161}. Golgi apparatus, trans-Golgi network {ECO:0000250|UniProtKB:Q9R1R2}. Cell projection, dendrite {ECO:0000250|UniProtKB:Q9R1R2}. |
| Mouse PG classification | NA |
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