| Gene Information | |
|---|---|
| Gene Name | KCNE5 |
| Organism | Homo sapiens (Human) |
| Gene Length | 142 |
| Protein Names | Potassium voltage-gated channel subfamily E regulatory beta subunit 5 (AMME syndrome candidate gene 2 protein) (Potassium channel subunit beta MiRP4) (Potassium voltage-gated channel subfamily E member 1-like protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 18 ( ENSG00000176076 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q9UJ90 |
| Gene Card | KCNE5 |
| Uniprot ID | Q9UJ90 |
| Pfam | PF02060 |
| In ASD | no |
| Allosteric Prediction | no (-0.425003376) |
| Ortholog in Animals | Alpaca_ KCNE5 ( ortholog_one2one ) Dog_ KCNE5 ( ortholog_one2one ) Macaque_ KCNE5 ( ortholog_one2one ) Mouse_ Kcne1l ( ortholog_one2one ) Pig_ KCNE5 ( ortholog_one2one ) Rat_ Kcne5 ( ortholog_one2one ) Rabbit_ KCNE5 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | KCNE3 |
| Tissue | NA |
| Tissue Specificity | Highly expressed in heart, skeletal muscle, brain, spinal cord and placenta. {ECO:0000269|PubMed:10493825}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs17003955 rs1364685385 rs199924386 rs41312935 |
| Subcellular location [CC] | Membrane {ECO:0000269|PubMed:20533308}; Single-pass type I membrane protein {ECO:0000305}. |
| Mouse PG classification | NA |
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