| Gene Information | |
|---|---|
| Gene Name | PDGFR1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1106 |
| Protein Names | Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta platelet-derived growth factor receptor) (Beta-type platelet-derived growth factor receptor) (CD140 antigen-like family member B) (Platelet-derived growth factor receptor 1) (PDGFR-1) (CD antigen CD140b) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P09619 |
| Gene Card | PDGFRB |
| Uniprot ID | P09619 |
| Pfam | PF07679; PF00047; PF07714 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.075658(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1GQ5 (X-ray 2.20A ) 1H9O (X-ray 1.79A ) 1SHA (X-ray 1.50A ) 2IUI (X-ray 2.40A ) 2L6W (NMR - ) 2PLD (NMR - ) 2PLE (NMR - ) 3MJG (X-ray 2.30A ) |
| DBSNP | rs17110944 rs17853027 rs34586048 rs2229558 rs41287110 rs367543286 rs863224946 rs397509381 rs144050370 rs1554108211 rs35322465 rs397509382 |
| Subcellular location [CC] | Cell membrane; Single-pass type I membrane protein. Cytoplasmic vesicle. Lysosome lumen. Note=After ligand binding, the autophosphorylated receptor is ubiquitinated and internalized, leading to its degradation. |
| Mouse PG classification | NA |
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